PTGX insider trading

NasdaqGM Healthcare

Protagonist Therapeutics, Inc — scored insider trade history from SEC Form 4 filings, parsed and contextualised by FilingIQ.

Total Form 4 trades
384
Last 90 days
37
Buys / sells
3% / 30%
Market cap
$5.49B

About Protagonist Therapeutics, Inc

Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide, an injectable mimetic of hepcidin that is in phase 3 clinical trials for the treatment of polycythemia vera; Icotrokinra, an orally delivered investigational drug which is in phase 3 clinical trials indicated to block biological pathways targeted by marketed injectable antibody drugs; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company also develops IL-17 oral peptide antagonist PN-88,1 an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker that is in pre-clinical stage. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

Company website: www.protagonist-inc.com

PTGX insider activity at a glance

FilingIQ has scored 384 insider transactions for PTGX since Aug 16, 2016. The most recent filing in our index is dated May 12, 2026.

Across the full history, 13 open-market purchases and 116 open-market sales were filed under transaction codes P and S respectively. Compensatory share awards (code A) and option exercises (code M) are tracked separately and not counted here.

The average FilingIQ composite score on PTGX insider trades is 64.7/100, produced by FilingIQ's multi-factor Form 4 model. Model framework documented at methodology.

Latest PTGX Form 4 filings

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Frequently asked

How many insider trades does FilingIQ track for PTGX?
FilingIQ tracks 384 Form 4 insider transactions for PTGX (Protagonist Therapeutics, Inc), covering filings from Aug 16, 2016 onwards. 37 of those were filed in the last 90 days.
Are PTGX insiders net buyers or net sellers?
Across the full Form 4 history for PTGX, 13 transactions (3%) were open-market purchases and 116 (30%) were open-market sales. Compensatory awards and option exercises are filtered out of these counts.
Where does PTGX insider data come from?
Every transaction shown on this page is sourced directly from SEC EDGAR Form 4 filings. FilingIQ parses the raw XML, normalises insider identity across reporting variations, and scores each trade on its multi-factor composite model.
What sector is PTGX in?
Protagonist Therapeutics, Inc (PTGX) is classified in the Healthcare sector, specifically Biotechnology, with a current market capitalisation of $5.49B.

Methodology & sources

Every PTGX insider transaction shown on FilingIQ is parsed directly from a public SEC Form 4 XML filing. Insider identity is normalised across reporting variants (CIK changes, name spellings, related-party indirect holdings). The FilingIQ composite score is documented in full on the team page and algo disclosure. Not investment advice; see disclaimer.