How many insider trades does FilingIQ track for SEPN?

FilingIQ tracks 54 Form 4 insider transactions for SEPN (Septerna, Inc.), covering filings from Oct 28, 2024 onwards. 17 of those were filed in the last 90 days.

Are SEPN insiders net buyers or net sellers?

Across the full Form 4 history for SEPN, 19 transactions (35%) were open-market purchases and 8 (15%) were open-market sales. Compensatory awards and option exercises are filtered out of these counts.

Where does SEPN insider data come from?

Every transaction shown on this page is sourced directly from SEC EDGAR Form 4 filings. FilingIQ parses the raw XML, normalises insider identity across reporting variations, and scores each trade on its multi-factor composite model.

What sector is SEPN in?

Septerna, Inc. (SEPN) is classified in the Healthcare sector, specifically Biotechnology, with a current market capitalisation of $1.35B.

SEPN insider trading

Healthcare

Septerna, Inc. — scored insider trade history from SEC Form 4 filings, parsed and contextualised by FilingIQ.

Total Form 4 trades

Last 90 days

Buys / sells

35% / 15%

Market cap

$1.35B

About Septerna, Inc.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves' disease and thyroid eye disease. The company also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders, including obesity and type 2 diabetes. In addition, it focuses on other therapeutic areas, including neurology, women's health, cardiovascular disease, and respiratory disease. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

Company website: septerna.com

SEPN insider activity at a glance

FilingIQ has scored 54 insider transactions for SEPN since Oct 28, 2024. The most recent filing in our index is dated Apr 15, 2026.

Across the full history, 19 open-market purchases and 8 open-market sales were filed under transaction codes P and S respectively. Compensatory share awards (code A) and option exercises (code M) are tracked separately and not counted here.

The average FilingIQ composite score on SEPN insider trades is 56.9/100, produced by FilingIQ's multi-factor Form 4 model. Model framework documented at methodology.

View live SEPN trades on FilingIQ Raw filings on SEC EDGAR

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Frequently asked

How many insider trades does FilingIQ track for SEPN?: FilingIQ tracks 54 Form 4 insider transactions for SEPN (Septerna, Inc.), covering filings from Oct 28, 2024 onwards. 17 of those were filed in the last 90 days.
Are SEPN insiders net buyers or net sellers?: Across the full Form 4 history for SEPN, 19 transactions (35%) were open-market purchases and 8 (15%) were open-market sales. Compensatory awards and option exercises are filtered out of these counts.
Where does SEPN insider data come from?: Every transaction shown on this page is sourced directly from SEC EDGAR Form 4 filings. FilingIQ parses the raw XML, normalises insider identity across reporting variations, and scores each trade on its multi-factor composite model.
What sector is SEPN in?: Septerna, Inc. (SEPN) is classified in the Healthcare sector, specifically Biotechnology, with a current market capitalisation of $1.35B.

Methodology & sources

Every SEPN insider transaction shown on FilingIQ is parsed directly from a public SEC Form 4 XML filing. Insider identity is normalised across reporting variants (CIK changes, name spellings, related-party indirect holdings). The FilingIQ composite score is documented in full on the team page and algo disclosure. Not investment advice; see disclaimer.