SPRB insider trading
HealthcareSPRUCE BIOSCIENCES, INC. — scored insider trade history from SEC Form 4 filings, parsed and contextualised by FilingIQ.
About SPRUCE BIOSCIENCES, INC.
Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure, and SPR204, a monoclonal antibody antagonist for Post-Bariatric Hypoglycemia. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.
Company website: sprucebio.com
SPRB insider activity at a glance
FilingIQ has scored 167 insider transactions for SPRB since Oct 14, 2020. The most recent filing in our index is dated Mar 9, 2026.
Across the full history, 12 open-market purchases
and 12 open-market sales
were filed under transaction codes P and S respectively. Compensatory share awards
(code A) and option exercises (code M) are tracked separately and not counted here.
The average FilingIQ composite score on SPRB insider trades is 60.4/100, produced by FilingIQ's multi-factor Form 4 model. Model framework documented at methodology.
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Frequently asked
- How many insider trades does FilingIQ track for SPRB?
- FilingIQ tracks 167 Form 4 insider transactions for SPRB (SPRUCE BIOSCIENCES, INC.), covering filings from Oct 14, 2020 onwards. 1 of those were filed in the last 90 days.
- Are SPRB insiders net buyers or net sellers?
- Across the full Form 4 history for SPRB, 12 transactions (7%) were open-market purchases and 12 (7%) were open-market sales. Compensatory awards and option exercises are filtered out of these counts.
- Where does SPRB insider data come from?
- Every transaction shown on this page is sourced directly from SEC EDGAR Form 4 filings. FilingIQ parses the raw XML, normalises insider identity across reporting variations, and scores each trade on its multi-factor composite model.
- What sector is SPRB in?
- SPRUCE BIOSCIENCES, INC. (SPRB) is classified in the Healthcare sector, specifically Biotechnology, with a current market capitalisation of $65.47M.
Methodology & sources
Every SPRB insider transaction shown on FilingIQ is parsed directly from a public SEC Form 4 XML filing. Insider identity is normalised across reporting variants (CIK changes, name spellings, related-party indirect holdings). The FilingIQ composite score is documented in full on the team page and algo disclosure. Not investment advice; see disclaimer.