How many insider trades does FilingIQ track for UPB?

FilingIQ tracks 27 Form 4 insider transactions for UPB (Upstream Bio, Inc.), covering filings from Oct 15, 2024 onwards. 5 of those were filed in the last 90 days.

Are UPB insiders net buyers or net sellers?

Across the full Form 4 history for UPB, 5 transactions (19%) were open-market purchases and 5 (19%) were open-market sales. Compensatory awards and option exercises are filtered out of these counts.

Where does UPB insider data come from?

Every transaction shown on this page is sourced directly from SEC EDGAR Form 4 filings. FilingIQ parses the raw XML, normalises insider identity across reporting variations, and scores each trade on its multi-factor composite model.

What sector is UPB in?

Upstream Bio, Inc. (UPB) is classified in the Healthcare sector, specifically Biotechnology, with a current market capitalisation of $524.71M.

UPB insider trading

NasdaqGS Healthcare

Upstream Bio, Inc. — scored insider trade history from SEC Form 4 filings, parsed and contextualised by FilingIQ.

Total Form 4 trades

Last 90 days

Buys / sells

19% / 19%

Market cap

$524.71M

About Upstream Bio, Inc.

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 clinical development for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps, and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Company website: upstreambio.com

UPB insider activity at a glance

FilingIQ has scored 27 insider transactions for UPB since Oct 15, 2024. The most recent filing in our index is dated Mar 16, 2026.

Across the full history, 5 open-market purchases and 5 open-market sales were filed under transaction codes P and S respectively. Compensatory share awards (code A) and option exercises (code M) are tracked separately and not counted here.

The average FilingIQ composite score on UPB insider trades is 62.6/100, produced by FilingIQ's multi-factor Form 4 model. Model framework documented at methodology.

View live UPB trades on FilingIQ Raw filings on SEC EDGAR

Latest UPB Form 4 filings

Sutherland Everett Rand Chief Executive Officer

S Mar 16, 2026

GRAY MICHAEL CFO and COO

S Mar 16, 2026

Most recent disclosures. Sign up to filter by score, transaction code, or insider role.

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Top insiders trading UPB

Sutherland Everett Rand

3 trades · score 73.0

GRAY MICHAEL

3 trades · score 72.0

Frequently asked

How many insider trades does FilingIQ track for UPB?: FilingIQ tracks 27 Form 4 insider transactions for UPB (Upstream Bio, Inc.), covering filings from Oct 15, 2024 onwards. 5 of those were filed in the last 90 days.
Are UPB insiders net buyers or net sellers?: Across the full Form 4 history for UPB, 5 transactions (19%) were open-market purchases and 5 (19%) were open-market sales. Compensatory awards and option exercises are filtered out of these counts.
Where does UPB insider data come from?: Every transaction shown on this page is sourced directly from SEC EDGAR Form 4 filings. FilingIQ parses the raw XML, normalises insider identity across reporting variations, and scores each trade on its multi-factor composite model.
What sector is UPB in?: Upstream Bio, Inc. (UPB) is classified in the Healthcare sector, specifically Biotechnology, with a current market capitalisation of $524.71M.

Methodology & sources

Every UPB insider transaction shown on FilingIQ is parsed directly from a public SEC Form 4 XML filing. Insider identity is normalised across reporting variants (CIK changes, name spellings, related-party indirect holdings). The FilingIQ composite score is documented in full on the team page and algo disclosure. Not investment advice; see disclaimer.